Quercetin Synergetic Complex

Ingredients

In synergy with Bromelain, NAC, Vitamin C, Nettle, Yarrow & Sarsaparilla

Health Benefits

• A powerful antioxidant that fights free radicals.
• Reduce chronic and acute inflammation.
• It reduces early morning stiffness, morning pain, and after-activity pain in people with rheumatoid arthritis.
• It contains anti-cancer properties that might help prevent the spread of cancerous cells and tumour growth.
• It may help prevent neurodegenerative diseases like Alzheimer’s and Parkinson’s.
• The anti-allergy properties of Quercetin help in the treatment of bronchitis and asthma. Quercetin is an effective antihistamine, which restricts histamine from being released from cells.
• Quercetin has antibacterial properties, which are effective against almost all types of bacteria.
• Quercetin help fights off viruses.
• Reduce the risk of heart disease and lowering high blood pressure.
• Quercetin assists in treating metabolic diseases like diabetes, hyperlipidemia, and nonalcoholic fatty liver disease.  
• Control blood sugar – Reduce fasting blood sugar levels and protect against complications of diabetes.
• Quercetin helps insulin secretion, enhances insulin resistance, lowers blood lipid levels, and inhibits inflammation and oxidative stress.
• Autoimmune disease. Quercetin is used for treating and preventing autoimmune diseases due to its anti-inflammation, anti-oxidation, and neuroprotective benefits.
• Quercetin positively treats rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, and lupus.
• Bromelain – Bromelain improves the absorption of Quercetin. Because it enhances absorption, bromelain helps to move Quercetin from the digestive tract into the bloodstream. Bromelain is also a highly effective anti-inflammatory in its own right.
• Vitamin C potentiates Quercetin’s activity by recycling it back to its reduced form. This increases Quercetin’s bioavailability and effectiveness as an antioxidant.
• N-acetyl cysteine (NAC) supports healthy glutathione status and will shunt Quercetin down safer metabolic pathways.
• Stinging Nettle Leaf – Assist in alleviating rheumatoid arthritis symptoms. This action may be due to the nettle leaf’s ability to lower the level of the inflammatory compound TNF-alpha in the body.
• Yarrow – May assist in the treatment of multiple sclerosis. It has anti-inflammatory properties, purifies the blood, and reduces joint and muscle inflammation.
• Sarsaparilla – Sarsaparilla is often recommended for gout, arthritis, and skin disorders. The saponins in the plant are believed to purify the blood and reduce joint and muscle inflammation.
• When taken Quercetin Complex together, these nutrients & herbs have a synergistic effect beyond what any of them can provide individually. It offers safe and effective immune support through its influence on improved barrier function, NK cell activity, and B-cell and T-cell maturation and differentiation.

Ingredients Health Benefits

Quercetin

Powerful antioxidant

Reduce chronic and acute inflammation. Quercetin reduces markers of inflammation in cells, including tumour necrosis factor-alpha(TNFa) and interleukin-6 (IL-s). It facilitates early morning stiffness, morning pain, and after-activity pain in people with rheumatoid arthritis. Quercetin has been demonstrated to alleviate the neuralgia and the inflammatory response of the sciatic nerve and spinal dorsal horn in rats with chronic constriction injury.

Anti-cancer properties

It contains anti-cancer properties that might help prevent the spread of cancerous cells and tumour growth. It suppresses cell growth and induces cell death in prostate cancer cells. It similarly affects the liver, lung, breast, bladder, blood, colon, ovarian, lymphoid, and adrenal cancer cells.

Neurogenerative Disease

It may help prevent neurodegenerative diseases like Alzheimer’s and Parkinson’s. Quercetin protects against oxidative stress and the toxic effect of certain metals on the nervous system. Oxidative stress and certain metals contribute to the development of neurodegenerative disease. Oxidative stress occurs when there is an imbalance of free radicals in the body. The antioxidant properties of quercetin help fight free radicals.

Anti-allergy

The anti-allergy properties of Quercetin help in the treatment of bronchitis and asthma. Quercetin is an effective antihistamine, which restricts histamine from being released from cells.

Antibacterial

Quercetin has antibacterial properties, which are effective against almost all types of bacteria, particularly those linked to the stomach, intestines, skin, respiratory, and urinary systems.

Antiviral

Quercetin and other flavonoids might help fight off viruses, such as adenovirus, herpes simplex virus, encephalitis, and respiratory syncytial virus.

Heart Health

Reduce the risk of heart disease and lowering high blood pressure. Quercetin improves blood vessel cell health and blood flow through arteries in people with heart disease. It reduces blood pressure and lower levels of harmful cholesterol in the blood. It has a relaxing effect on blood vessels.

Regulate Blood Sugar

Control blood sugar – Reduce fasting blood sugar levels and protect against complications of diabetes. 

Quercetin also treats metabolic diseases like diabetes, hyperlipidemia, and nonalcoholic fatty liver disease.  Quercetin helps insulin secretion, enhances insulin resistance, lowers blood lipid levels, inhibits inflammation and oxidative stress, alleviates hepatic lipid accumulation, and regulates gut microbiota.

Autoimmune disease.

Quercetin is used for treating and preventing autoimmune diseases which appear to result from a breakdown and dysregulation of the immune system. Quercetin shows promise in this area due to its anti-inflammation, anti-oxidation, and neuroprotective benefits. Studies of late heralded positive effects of Quercetin on rheumatoid arthritis, inflammatory bowel disease, multiple sclerosis, and lupus.

Stinging Nettle

Assist in alleviating rheumatoid arthritis symptoms. This action may be due to the nettle leaf’s ability to lower the level of the inflammatory compound TNF-alpha in the body. Nettle leaf alters the genetic transcription of nuclear factor kappa beta (NFkB), thereby decreasing inflammation of synovial tissue in the joints. Nettle leaf extract also suppresses the development of dendritic cells that stimulate T-cells to release inflammatory chemicals. This may contribute to the therapeutic effect of nettle leaf extract on T cell-mediated inflammatory diseases like Rheumatoid arthritis.

Yarrow 

May assist in the treatment of multiple sclerosis. It has anti-inflammatory properties, purifies the blood, and reduces joint and muscle inflammation.

Sarsaparilla

Sarsaparilla is often recommended for gout, arthritis, and skin disorders. In years past, it was even considered the gold treatment standard for syphilis. The saponins in the plant are believed to purify the blood and reduce joint and muscle inflammation.

Bromelain

 Quercetin’s bioavailability is low, and it can be challenging to get the right amount in our tissues. Bromelain improves the absorption of Quercetin. Bromelain is a plant-based protein-digesting enzyme that breaks down proteins into constituent amino acids. Because it enhances absorption, bromelain helps to move Quercetin from the digestive tract into the bloodstream. A clinically effective dose of bromelain enhances quercetin absorption, and it magnifies the efficacy of Quercetin. Bromelain is also a highly effective anti-inflammatory in its own right. It can help to relieve joint and connective tissue pain for athletes and reduce C-reactive protein, the inflammation marker. Bromelain also directly supports athletic performance by facilitating protein assimilation. Protein is essential for tissue repair, muscle formation, and every metabolic enzyme in the body. Bromelain frees up amino acids, the protein building blocks, so they are better absorbed. Additionally, research confirms that bromelain induces the breakdown of stored fat, which provides steady energy for athletic activity.

Vitamin C 

potentiates Quercetin’s activity by recycling it back to its reduced form. This increases Quercetin’s bioavailability and effectiveness as an antioxidant.

N-acetyl cysteine (NAC) 

Supports healthy glutathione status and will shunt Quercetin down safer metabolic pathways.

Anti-inflammatory and antioxidative properties of Quercetin

A major health benefit of Quercetin comes from its antioxidant (antioxidative) and anti-inflammatory properties. Inflammation is an essential immune response when facing pathogens (virus, bacteria, and fungus) or dangers (tissue damage caused by free radicals, cholesterol, amyloid-beta, or asbestos). One of the major innate defence mechanisms is the activation of the NLRP3 inflammasome (protein complexes in the cell that can sense signals from pathogens or dangers), leading to the production of IL-1β. This vital compound mediates many aspects of inflammatory responses.

However, dysregulated activations of inflammasome have been linked to the initiation and progression of immune and inflammatory disorders such as atherosclerosis, inflammatory diseases, type 2 diabetes, autoimmune diseases, Alzheimer’s disease, and obesity, as well as collateral tissue damages that occur during infections.

Quercetin has been shown to modulate NLRP3 inflammasome. In several experimental models of inflammatory conditions (including infections), Quercetin reduced the production of reactive oxygen species. It inhibited the overexpression of different components of the NLRP3 inflammasome, resulting in reduced activation of the NLRP3 inflammasome and decreased secretion of IL-1β.

Quercetin can also neutralize reactive oxygen species that increase ER stress and mitochondrial dysfunction, activating the NLRP3 inflammasome. Further, Quercetin suppresses the NF-κB pathway, leading to reduced activation of NLRP3. Quercetin is involved in multiple pathways leading to modulation of NLRP3 inflammasome and reducing downstream pro-inflammatory cytokine levels.

Quercetin’s role in regulating immunity

• Quercetin reduced TNF-α production in macrophages and lung epithelial cells when stimulated by LPS, an endotoxin found in bacteria that triggers an immune response. This suggests Quercetin modulates TNF-α-mediated induction of inflammatory cascades.
• Quercetin exhibited a regulatory effect on several properties of immune cells, such as inhibiting histamine and cytokine release from mast cells and inducing gene expression and production of Th-1-derived interferon (IFN)-g, as well as downregulating Th-2-derived IL-4 production by normal peripheral blood mononuclear cells. This suggests Quercetin may have anti-allergic properties.
• Quercetin inhibited cells from being infected with influenza virus, Zika virus, and Ebola virus via interaction with viral hemagglutinin protein inhibited virus entry into the cell or reduced virus replication. This suggests Quercetin has antiviral properties.

Quercetin’s antioxidant, anti-inflammatory, and immunomodulatory properties have inspired researchers to investigate its clinical effects. Quercetin supplementation of 500 mg/day significantly reduced fasting plasma glucose among patients with metabolic syndrome and related disorders, showed a small but significant impact on circulating C-reactive protein levels, and significantly reduced blood pressure. Also, a higher dose of Quercetin has been shown to reduce upper respiratory tract infection severity and sick days in older adults.

Quercetin suppresses DC activation and thus may potentially be used for the prevention and treatment of inflammation, autoimmunity, and transplantation.